Autologous Mitochondrial Transplant for Cerebral Ischemia
ConditionCerebral Ischemia
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-85
SponsorUniversity of Washington
About this trial
The investigators propose to infuse healthy autologous mitochondria into cerebral vessels supplying brain tissue experiencing ischemia in patients who undergo standard-of- care endovascular reperfusion therapy.
Eligibility criteria
Qualifiers
Eligible for endovascular thrombectomy to treat acute large vessel occlusion
Eligible for angioplasty (microcatheter-based balloon/mechanical and chemical angioplasty) to treat acute cerebral vasospasm after aneurysmal subarachnoid hemorrhage
Subjects for whom there is likely to be enough time to obtain meaningful consent from patient or legally-authorized representative
Disqualifiers
Unable to receive a brain MRI scan
Known mitochondrial disease
Hemodynamically unstable patients in whom standard of care endovascular reperfusion treatment cannot safely be performed or completed
Trial design
Treatments tested in this trial
- Endovascular autologous mitochondrial transplantation
Treatment groups
20 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov