Autologous Ovarian Tissue Transplantation
ConditionFemale Infertility
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-45
SponsorUniversity of Pittsburgh
About this trial
Chemotherapy and radiation for cancer and other conditions can cause infertility. Several centers around the world are cryopreserving ovarian tissue from these patients though an experimental protocol, including the Fertility Preservation Program in Pittsburgh (protocol PRO08050491). The objective of this study is to study the efficacy and safety of autologous tissue transplantation in patients diagnosed with primary ovarian insufficiency after chemotherapy and/or radiation treatments.
Eligibility criteria
Qualifiers
Previously cryopreserved ovarian tissue
Ovarian insufficiency and/or candidate for pregnancy
Good health
Oncologist's clearance
Disqualifiers
Patients considered to be high risk for surgical complications
Women with contraindication for pregnancy if goal is to achieve pregnancy
Women positive for the BRCA mutations
Women with a history of leukemia, ovarian cancer or a cancer that likely involved ovaries at the time of ovarian tissue collection
Trial design
Treatments tested in this trial
- Ovarian tissue transplant
Treatment groups
5 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov