Autologous Tenon's Capsule Graft for Refractory Macular Holes
ConditionMacular Hole Surgery
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorBenha University
About this trial
This prospective interventional study evaluates the anatomical and functional outcomes of autologous Tenon's capsule grafting in patients with refractory full-thickness macular holes. Eligible patients include those with chronic large macular holes (\>400 µm) or persistent holes following prior pars plana vitrectomy with internal limiting membrane peeling and gas tamponade. Anatomical closure will be assessed using spectral-domain optical coherence tomography, and functional outcomes will be evaluated by best-corrected visual acuity over a 3-month follow-up period.
Eligibility criteria
Qualifiers
Age 18 years or older
Chronic macular hole >400 µm, or
Persistent macular hole following prior vitrectomy with ILM peeling and gas tamponade
Clear ocular media and adequate fixation for OCT imaging
Disqualifiers
Active ocular infection or inflammation
Advanced glaucoma or optic neuropathy
History of intraocular tumors
Severe proliferative vitreoretinopathy
Trial design
Treatments tested in this trial
- Autologous Tenon's Capsule Graft Placement
Treatment groups
20 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov