Autologous Testicular Tissue Transplantation
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age18-50
SponsorUniversitair Ziekenhuis Brussel
About this trial
Freezing testicular tissue of prepubertal boys is a method for preserving spermatogonial stem cells in case of imminent gonadotoxic treatment during childhood. In case of total azoospermia or absence of spermatozoa that can be used for intra-cytoplasmic injection (ICSI) in adulthood, the investigators intend to perform the first in men autologous testicular tissue transplantation to restore fertility.
Eligibility criteria
Qualifiers
At least 18 years old
In case of female partner, age < 43 year
Absence of spermatozoa that can be used for ICSI on 2 semen analyses
Normal standardised preliminary and preoperative bloodsampling results
Disqualifiers
Risk for presence of malignant cells in the testicular tissue
Contra-indication for surgery
Contra-indication for pregnancy in the female partner
BMI > 32
Trial design
Treatments tested in this trial
- Autologous testicular tissue transplantation of prepubertal frozen testicular tissue
Treatment groups
5 Participants
are divided into 1 treatment groupSponsors and collaborators
Universitair Ziekenhuis Brussel
Lead sponsor
Vrije Universiteit Brussel
Collaborator
Source ClinicalTrials.gov