Autopsy and Photon Counting Computed Tomography to Evaluate Thromboses Related to Central Venous Catheters

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorThomas Kander

About this trial

Central venous (CVC) is essential in modern healthcare but unfortunately associated with complications, including thrombosis. In a recently published study, it was showed that 12 out of 12 deceased patients had subclinical CVK-related thrombosis (Rockholt et al.). To shed light on this problem, the current studies were designed. In sub-study 1, deceased patients with CVC who are referred for clinical autopsy are included. Before the autopsy, the deceased will be examined with a photon-counting computed tomography (CT) scan and the results will be compared.

In sub-study 2, living patients with CVC who are referred for various CT scans without contrast, are included. After informed consent, the patient will be examined with the photon-counting CT, whose reliability has been validated in Part 1 and the incidence of subclinical CVC-related thrombosis will be reported.

Eligibility criteria

Qualifiers

Diseased patients with an indwelling central venous catheter and a clinical indication for autopsy

Informed and signed consent from next of kind

Disqualifiers

None

Living patients with an indwelling central venous catheter who are referred to a CT scan without iv contrast

Informed and signed consent from the patient

Trial design

Treatments tested in this trial

  • Diseased patients with an indwelling central venous catheter who is referred to autopsy
  • Living patients with an indwelling central venous catheter referred to a CT scan without iv contrast

Treatment groups

75 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Thomas Kander

Lead sponsor

Region Skane

Sponsor institution