About this trial
The goal of this clinical trial is to determine if adding avocados to the diet of impacts cognition in 70 older adults, age 65-85, without dementia. We will test for change in functional MRI, cognitive performance, and brain blood flow. Intervention group participants will be asked to consume 1 avocado per day for 12 weeks. Participants in the control group will be asked to continue their normal intake for 12 weeks. Throughout the study, participants will be asked to perform cognitive tests, MRI, blood tests, and questionnaires.
Eligibility criteria
Qualifiers
Males and females aged 65-85 years
Good general health with no concomitant disease
BMI 18.5 - 35 kg/m2
Mini Mental State Exam ≥26
Disqualifiers
Unwilling or unable to consume avocado
Latex allergy
Consistently taking lutein + zeaxanthin supplements
Skin carotenoid content ≥400
Trial design
Treatments tested in this trial
- Avocado Group
Treatment groups
Sponsors and collaborators
University of Kansas Medical Center
Lead sponsor
Avocado Nutrition Center
Collaborator