Axillary Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Patients With Initial cN1 Breast Cancer

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorHenan Cancer Hospital

About this trial

SLNB has been recommended by domestic and foreign guidelines for patients with initial cN1 and NAC descending to ycN0. However, the best technical path is still not very clear at present, and the long-term tumor safety data is still insufficient. Therefore, it is necessary to further explore the optimal technical pathway and long-term tumor safety for SLNB in patients with initial cN1 and NAC downgrading to ycN0 in the real world.This study will evaluate the optimized technical pathway and long-term tumor safety of SLNB in patients with initial cN1 and NAC downgrading to ycN0 in real-world studies.

Eligibility criteria

Qualifiers

Patients With ECOG Score 0-1 Points

Patients With Breast Cancer Stage cT1-3N1M0 (According to AJCC Version 7) Pathological Diagnosis of Ipsilateral Axillary Lymph Node Metastasis in Patients With Invasive Breast Cancer

Patients With Abnormal Axillary Lymph Nodes ≤ 3 Detected by Imaging Examination

Patients With Effective Neoadjuvant Therapy (CR+PR)

Disqualifiers

Stage IV (metastatic) breast cancer;

Simultaneous double breast cancer;

Baseline cT4;

Baseline cN2-3

Trial design

Treatments tested in this trial

  • SLNB group

Treatment groups

508 Participants
are divided into 1 treatment group

Sponsors and collaborators