Basal Instincts: Towards Better Understanding of Basal Cell Function in Chronic Rhinosinusitis With Nasal Polyps

ConditionsChronic Rhinosinusitis With Nasal Polyps Allergic Rhinitis

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorUniversitaire Ziekenhuizen KU Leuven

About this trial

During this project, the investigators want to explore in vitro changes in basal cells and the crosstalk with residing immune cells as potential pathogenic mechanisms in CRSwNP vs healthy controls by using surgically resected patient samples.

Eligibility criteria

Qualifiers

Patients over the age of 18

Males and females

Disqualifiers

CRSwNP

Smoker, or < 1-year ex-smoker

Underlying systematic pathology (Morbus Wegener or Churg Strauss Syndrome for example)

Trial design

Treatments tested in this trial

Conchotomy, aesthetic nose surgery or functional endoscopic sinus operation

Treatment groups

300 Participants

are divided into 3 treatment groups

Sponsors and collaborators

Universitaire Ziekenhuizen KU Leuven

Lead sponsor

Regeneron Pharmaceuticals

Collaborator

Source ClinicalTrials.gov