Baylor Infant and Toddler Biomarker of Nutrition Study

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age3-24
SponsorBaylor College of Medicine

About this trial

Young children rely on their foods and drinks for the nutrients they need to grow, like energy, protein, vitamins, and minerals. In addition to nutrients, there are substances in fruits, vegetables, milk and formula, called phytochemicals, that can support health. While researchers know more about the role of phytochemicals in adult health, researchers know surprisingly little about how phytochemicals can support health in young children. One group of phytochemicals are called the carotenoids. Carotenoids are responsible for the red, orange, and yellow colors in some fruits and vegetables. In adults, carotenoids can support visual function. Researchers also know that measuring levels of carotenoids in the blood or optically in the skin, can serve as an indirect measurement of what child and adults eat.

The purpose of this study is to determine how a child's usual intake of carotenoids is related to their visual development and their blood and skin levels of carotenoids. The study involves 6 visits. For each visit, we will ask about the child's recent diet, will measure their body size, collect a blood sample, collect optical measurements of their skin, and will test how sharp their vision is.

Eligibility criteria

Qualifiers

healthy

born at term (more than or equal to 37 weeks gestation)

between the 1st to 99th weight for age percentile at 3 months of age

participating guardian speaks, reads, and understands English

Disqualifiers

physician-diagnosed metabolic, absorptive, or endocrine condition

diagnosed food intolerance or allergy

has a sibling enrolled in the study

Trial design

Treatments tested in this trial

  • Carotenoid Intake
  • Serum carotenoid concentrations

Treatment groups

208 Participants
are divided into 1 treatment group

Sponsors and collaborators

Baylor College of Medicine

Lead sponsor

University of Houston

Collaborator

East Carolina University

Collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Collaborator