About this trial
This study meets the NIH definition of a clinical trial, but is not a treatment study. Instead, the goal of this study is to investigate how hearing ourselves speak affects the planning and execution of speech movements. The study investigates this topic in both typical speakers and in patients with Deep Brain Stimulation (DBS) implants. The main questions it aims to answer are:
* Does the way we hear our own speech while talking affect future speech movements? * Can the speech of DBS patients reveal which brain areas are involved in adjusting speech movements? Participants will read words, sentences, or series of random syllables from a computer monitor while their speech is being recorded. For some participants, an electrode cap is also used to record brain activity during these tasks. And for DBS patients, the tasks will be performed with the stimulator ON and with the stimulator OFF.
Eligibility criteria
Qualifiers
native speaker of American English
no communication or neurological problems (except for subjects in the DBS group)
250-4000 Hz pure tone hearing thresholds equal to or better than 25 dB HL for children and young adults and equal to or better than 35 dB HL for older adults
no medications that affect sensorimotor functioning (except for in the DBS group)
Disqualifiers
None
Trial design
Treatments tested in this trial
- Auditory feedback perturbation during speech
- Visual feedback perturbation during reaching
- DBS stimulation ON/OFF
Treatment groups
Sponsors and collaborators
University of Washington
Lead sponsor
National Institutes of Health (NIH)
Collaborator
National Institute on Deafness and Other Communication Disorders (NIDCD)
Collaborator