Beyond MARS: Magnetic Resonance Study: A Novel Assessment of Placental Perfusion During Pregnancy

ConditionPregnancy
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-60
SponsorEndeavor Health

About this trial

The purpose of this study is to evaluate the flow of oxygen and blood necessary for nutrient transfer across the placenta during the second and third trimesters in pregnancy in women who are obese before pregnancy compared to women who have an average weight before pregnancy.

This study will evaluate blood flow across the placenta by functional Magnetic Resonance Imaging (fMRI). The investigators hypothesize that there will be differences in placental oxygenation and blood flow among women with obesity as compared to those with normal weight.

Participants will be asked to complete:

* MRI in the second trimester (20-24 weeks) * MRI in the third trimester (30-34 weeks)

Eligibility criteria

Qualifiers

Singleton pregnancy, less than 24 weeks gestation

Pre-pregnancy BMI between 18.5 - 24.9kg/m2 or ≥30kg/m2

Disqualifiers

Asthma on controller medication

Autoimmune Conditions

Chronic Hypertension

Claustrophobia

Trial design

Treatments tested in this trial

  • functional Magnetic Resonance Imaging (fMRI)

Treatment groups

30 Participants
are divided into 2 treatment groups

Sponsors and collaborators