About this trial
The purpose of this study is to evaluate the flow of oxygen and blood necessary for nutrient transfer across the placenta during the second and third trimesters in pregnancy in women who are obese before pregnancy compared to women who have an average weight before pregnancy.
This study will evaluate blood flow across the placenta by functional Magnetic Resonance Imaging (fMRI). The investigators hypothesize that there will be differences in placental oxygenation and blood flow among women with obesity as compared to those with normal weight.
Participants will be asked to complete:
* MRI in the second trimester (20-24 weeks) * MRI in the third trimester (30-34 weeks)
Eligibility criteria
Qualifiers
Singleton pregnancy, less than 24 weeks gestation
Pre-pregnancy BMI between 18.5 - 24.9kg/m2 or ≥30kg/m2
Disqualifiers
Asthma on controller medication
Autoimmune Conditions
Chronic Hypertension
Claustrophobia
Trial design
Treatments tested in this trial
- functional Magnetic Resonance Imaging (fMRI)