About this trial
Healthy aging is typically accompanied by diminished capability for learning and retrieval of high-fidelity long-term memory (LTM). The decline in these faculties is accelerated and becomes significant deficits in LTM and cognitive control functions at the level or a diagnosis of Mild Cognitive Impairment (MCI). Training with the navigation game, relative to training with control games, is expected to improve LTM performance for older adult participants.
Researchers will compare two different digital interventions to assess whether they may be helpful in improving cognitive function.
Participants will conduct study activities remotely (e.g., at-home):
1. Baseline Assessment. Complete a series of cognitive assessments and surveys. 2. Intervention. Engage in a digital intervention for up to 8 weeks. 3. Post Intervention Assessment. Complete the same cognitive assessments and surveys as the Baseline Assessment. 4. Follow-Up Assessment. Six months after the intervention ends, participants will complete the same cognitive assessments and surveys as the Baseline Assessment.
Eligibility criteria
Qualifiers
Minimum of 12 years of education
English fluency: All task instructions are presented in English language text. In order to control for sufficient and equivalent participant comprehension of the procedures and instructions, we require their self-report of fluency in English.
Normal or corrected-to-normal vision
Normal or corrected-to-normal hearing
Disqualifiers
Under the age of 60
Clinical diagnosis of neurological or psychiatric disorder Clinical diagnosis of dementia or AD8 score of >4
Visually or hearing impaired without correction to normal
Regularly (one or more times per week) practicing an instrument within the last year
Trial design
Treatments tested in this trial
- Long Term Memory
- Worder
Treatment groups
Sponsors and collaborators
University of California, San Francisco
Lead sponsor
National Institute on Aging (NIA)
Collaborator