Bioavailability of Aronia Melanocarpa
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorMaastricht University Medical Center
About this trial
The main objective of this study is to study the bioavailability and kinetics of acute Aronia Melanocarpa supplementation in healthy young (18-35 years) and older adults (55-75 years) adults. During the test day, participants will ingest a drink consisting of Aronia Melanocarpa extract (AME). The bioavailability and kinetics of AME will be assessed via frequent blood sampling, urine collection, and faecal sampling, in which AME and metabolite profiles will be quantified.
Eligibility criteria
Qualifiers
BMI between 18-35 kg/m2
Systolic blood pressure < 160 mmHg and diastolic blood pressure < 100 mmHg
Stable body weight (weight gain or loss < 3 kg in the past three months)
Willingness to give up being a blood donor from 8 weeks before the start of the study, during the study and for 4 weeks after completion of the study
Disqualifiers
Smoking or smoking cessation < 12 months
Severe medical conditions, including asthma, kidney failure, auto-inflammatory diseases, rheumatoid arthritis, diabetes mellitus, cardiovascular disease, gastrointestinal disorders such as Crohn's disease, colitis
Use of dietary supplements or medication affecting the main outcomes of the study (e.g. affecting gut metabolism, blood pressure medication)
Use of an investigational product within another biomedical intervention trial within the previous month
Trial design
Treatments tested in this trial
- Aronia Melanocarpa extract
Treatment groups
16 Participants
are divided into 1 treatment groupSponsors and collaborators
Maastricht University Medical Center
Lead sponsor
BioActor
Collaborator
Source ClinicalTrials.gov