Biocollection on Peripheral Inflammation

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorNantes University Hospital

About this trial

Most psychiatric research is based on the nosographic classifications used in current practice. At present, there is no diagnostic or prognostic biomarker for psychiatric pathologies commonly used in clinical practice. The study hypothesis is that peripheral inflammatory biomarkers could be common to several psychiatric disorders, in particular psychotic disorders (bipolar disorder, schizophreniform disorder, schizophrenia, depressive episode with psychotic features). The aim of this project is to set up a bio-collection of biological samples (peripheral blood samples) with associated phenotypic data (assessment of various symptoms using standardized scales in patients whose blood is sampled). The setting up of this cohort follows on from work carried out on a PsyCourse cohort also using a transdiagnostic approach in psychiatry, in order to be able to collaborate within a European research project.

Eligibility criteria

Qualifiers

Major patient

Characterized depressive episode with psychotic features,

Bipolar disorder type I

Bipolar disorder type II

Disqualifiers

Pregnant,

History of cancer in the last 5 years,

Vaccination within the last 4 weeks,

Acute or chronic infection,

Trial design

Treatments tested in this trial

  • Peripheral venipuncture blood sampling, as part of standard care procedures
  • Interview with a psychiatrist

Treatment groups

300 Participants
are divided into 1 treatment group

Sponsors and collaborators

Nantes University Hospital

Lead sponsor

CR2TI, INSERM, UMR1064

Collaborator