Biological Sex and CTEPH-related RV Dysfunction and Recovery (BIOSPHeRe)
ConditionCTEPH
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorIntermountain Health Care, Inc.
About this trial
1. To identify biological sex differences in baseline RV function in CTEPH 2. To identify biological sex differences in recovery of RV function after PTE surgery in CTEPH 3. To determine if sex hormone levels relate to RV function at CTEPH diagnosis and during recovery after PTE.
Eligibility criteria
Qualifiers
Adult (≥18 years old) patients diagnosed with CTEPH per current guideline standard42
Subject must have a baseline TTE (within 3 months of diagnosis) with adequate images for RVGLS analysis
Subject must have a right heart catheterization (RHC) at the time of diagnosis
To be included in the Aim 2 analysis, patients must undergo PTE surgery and have a TTE performed 3-9 months after surgery with adequate images for RVGLS strain analysis
Disqualifiers
Unclear or mixed PH diagnosis as designated by an expert clinician at Intermountain PH center
Any subjects <18 years of age
Patients diagnosed during pregnancy
Patients without a TTE and RHC at time of diagnosis
Trial design
Treatments tested in this trial
- Not listed
Trial groups
10 Participants
are grouped into 3 trial groupsSponsors and collaborators
Source ClinicalTrials.gov