Biology of Cerebral Arteriovenous Malformations and Prognosis of Cerebral Arteriovenous Malformations

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age0+
SponsorFondation Ophtalmologique Adolphe de Rothschild

About this trial

The cerebral arteriovenous malformations correspond to the formation of an entanglement of morphologically abnormal vessels called nidus, which shunt the blood circulation directly from the arterial circulation to the venous circulation.

The cerebral arteriovenous malformations are an important cause of hemorrhagic stroke.

The hypothesis is that cerebral haemorrhage associated with a cerebral arteriovenous malformations would come from peri-nidal micro-vessels, in connection with infiltration of leucocytes and / or defective maintenance of microvascular integrity by platelets.

Eligibility criteria

Qualifiers

Patient over 18 years old

Patient with a cerebral AVM for which an intervention (endovascular treatment or surgery) or only clinical monitoring

Express consent to participate in the study

children

Disqualifiers

Patient benefiting from a legal protection measure

Pregnant or breast feeding woman

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed