Biomarker of Diabetic Retinopathy
ConditionDiabetic Retinopathy
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorIndiana University
About this trial
Diabetic retinopathy (DR) is a complication of diabetes in which blood vessels supplying blood to the back of the eye (retina) are dysfunctional. This can lead to an improper supply of oxygen and nutrients to the retinal tissue, or it may trigger the formation of new blood vessels in response to the oxygen/nutrient deficiency. Ultimately affecting the normal vision. There is no known marker that will provide information on the health status of retinal blood vessels. Using highly specialized cells in the blood, this study will try to discover a marker of DR.
Eligibility criteria
Qualifiers
Ability to cooperate with imaging procedures.
Health status: established type 2 diabetes
No history of panretinal photocoagulation (PRP)
No history of treatment with intravitreal agents for past 12 months
Disqualifiers
Previous or current malignancy
Acute or chronic infection (HIV, hepatitis B or C, tuberculosis)
Cerebral vascular accident or cerebral vascular procedure
Current pregnancy
Trial design
Treatments tested in this trial
- Blood draw
Treatment groups
192 Participants
are divided into 6 treatment groups6
Treatment groupsSee each treatment group below.
Sponsors and collaborators
Source ClinicalTrials.gov