Biomarkers in Friedreich's Ataxia
ConditionFriedreich's Ataxia
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age6-70
SponsorUniversity of Florida
About this trial
The purpose of this project is to characterize measures of cardiac performance and neuromuscular physiology in FA patients using novel techniques, including echocardiography and magnetic resonance imaging (MRI), metabolic exercise testing, and neurophysiological outcomes.
Eligibility criteria
Qualifiers
Genetic diagnosis of Friedreich's ataxia by DNA sequencing, mutational analysis or protein assay OR be a healthy subject with no evidence of a neuromuscular disorder
Between the ages of 6 and 70 (inclusive)
Are able to tolerate metabolic exercise testing
Are stable on cardiac medication regimen for 3 months prior to screening
Disqualifiers
Presence of unstable heart disease
Receipt of cardiac transplant
Any concurrent medical condition which, in the opinion of the investigators, would make the subject unsuitable for the study
Trial design
Treatments tested in this trial
- Not listed
Trial groups
203 Participants
are grouped into 3 trial groupsSponsors and collaborators
University of Florida
Lead sponsor
Children's Miracle Network
Collaborator
National Institutes of Health (NIH)
Collaborator
National Center for Advancing Translational Sciences (NCATS)
Collaborator
Source ClinicalTrials.gov