Biomarkers of Endometrial Receptivity

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
AgeUp to 36
SponsorThe Institute of Molecular and Translational Medicine, Czech Republic

About this trial

Analysis of proteins from cervical mucus will be done in patients undergoing infertility treatment (fresh or frozen embryo transfer). Cervical mucus will be analysed for potential new biomarkers of endometrium receptivity. Comparison of the peptide spectrum will be done for the pregnant and not pregnant patients.

Eligibility criteria

Qualifiers

female aged less than 37 years (maximally 36y + 364d)

no smoker

normal menstrual cycles lasting between 25 to 35 days

had been infertile for less than five years

Disqualifiers

genetic disease

metabolic and/or endocrine disorders

polycystic ovary syndrome (defined by the Rotterdam criteria)

women with prior diagnosis of endometriosis or adenomyosis

Trial design

Treatments tested in this trial

  • Cervical mucus will be collected from patients undergoing IVF
  • Cervical mucus will be collected from patients undergoing transfer of cryopreserved embryos

Treatment groups

476 Participants
are divided into 2 treatment groups

Sponsors and collaborators

The Institute of Molecular and Translational Medicine, Czech Republic

Lead sponsor

University Hospital Olomouc

Collaborator

Brno University Hospital

Collaborator