Prediction of conduction disorders (CDs) in patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) is an important and complex process with a significant impact on patient outcomes. The goal of this observational prospective trial is to investigate the role of pre-procedural values of systemic biomarkers of inflammation and fibrosis in the prediction of new-onset CDs and permanent pacemaker implantation (PPI) in patients undergoing the TAVI procedure.
Written consent to participate in the trial
Diagnosis of severe AS according to current European Society of Cardiology (ESC) guidelines for valvular heart disease
Acute infectious disease
Chronic inflammatory or autoimmune disease
Corticosteroid or other immunosuppressive therapy
Active malignant disease
Clinical Hospital Center Rijeka
Lead sponsor
University of Rijeka, Medical Faculty
Collaborator