About this trial
Osteoarthritis (OA), the most common type of arthritis, affects more than 32.5 million adults in the United States. It is also among the most expensive condition to treat when joint replacement surgery is required. Although biomechanics plays an important role in OA disease, the non-surgical treatment options addressing biomechanics are scarce with limited effect. AposHealth is the fist biomechanical treatment that was shown to have a significant short-term effect on patients with knee OA.
The main objectives of this study are:
1. To assess AposHealth, a non-invasive home-based biomechanical treatment, as an alternative treatment for patients who are eligible for Total Knee Replacement (TKR). 2. To assess AposHealth as a new post-operative rehabilitation tool for patients post TKR.
Eligibility criteria
Qualifiers
Men or non-pregnant women
Between ages 45 and 80, inclusive
ACR clinical criteria for OA of the knee
Symptomatic uni- or bilateral OA of the knee for at least six months
Disqualifiers
Body Mass Index (BMI) > 40
History of an inflammatory rheumatic disease
Non-knee musculoskeletal pain that is more severe than the knee pain
Corticosteroids injections in the knees in the previous 6 weeks
Trial design
Treatments tested in this trial
- AposHealth
- Total Knee Replacement (TKR)
Treatment groups
Sponsors and collaborators
Geisinger Clinic
Lead sponsor
Apos Medical and Sports Technology Ltd.
Collaborator