Blast Overpressure Longitudinal Study
ConditionLow-level Blast Exposure
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-50
SponsorUniformed Services University of the Health Sciences
About this trial
The goal of this observational study is to learn about the impact of low-level blast exposure in U.S. Special Operations Forces personnel. The main questions it aims to answer are:
What advanced brain imaging changes are related to clinical presentation after low-level blast exposure? What are the relationships between low-level blast exposure and common groups of symptoms after concussion?
Participants will:
* Undergo advanced brain imaging * Answer questionnaires * Complete clinical tests * Provide blood, urine, and saliva samples * Wear blast sensors
Eligibility criteria
Qualifiers
Active duty
U.S. SOF personnel
18-50 years old
Disqualifiers
Subjects will be excluded only if their participation will significantly interfere with validity of data collection or safety during the study (e.g., they have conditions that might result in harm or injury during research procedures).
Example: pregnancy (balance considerations)
Example: being unable to undergo MRI testing (i.e., they have non-MRI compatible devices, imbedded metal fragments such as shrapnel, and/or severe claustrophobia; these MRI contraindications will be screened using an MRI Safety Questionnaire)
Trial design
Treatments tested in this trial
- Not listed
Trial groups
250 Participants
are grouped into 2 trial groupsSponsors and collaborators
Uniformed Services University of the Health Sciences
Lead sponsor
The Geneva Foundation
Collaborator
MIT Lincoln Laboratory
Collaborator
Source ClinicalTrials.gov