Bleeding of Unknown Cause: a Swiss Case-control Study
ConditionBleeding Disorder
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age16-65
SponsorUniversity Hospital, Geneva
About this trial
The goal of this prospective cohort is to identified specific biological patterns in patients with a bleeding of unknown cause and to study the specific mechanisms of the bleeding disorder for each subset of patients.
Eligibility criteria
Qualifiers
Man with ISTH BAT>3. If the calculated score includes a surgical bleeding, then two other items of the score should be >0
Woman with ISTH BAT >5 points. If the calculated score includes a surgical or a postpartum bleeding, then two other items of the score should be >0
Disqualifiers
Ongoing pregnancy
Intake of antithrombotic treatment or non-steroidal anti-inflammatory drugs for least 10 days at time of blood collection
Intake of antifibrinolytic or blood product administration (factor concentrate, frozen fresh plasma, prothrombin complex concentrate) for least 14 days before blood collection
Active cancer (defined as cancer diagnosis within the last five years or treatment within the two last years before study inclusion)
Trial design
Treatments tested in this trial
- Thrombin generation
- Fibrinolysis
- Fibrin clot structure
- Coated platelets
Treatment groups
400 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov