Blood Flow Restriction Training for Age-Related Sarcopenia

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age65-100
SponsorWest China Hospital

About this trial

Brief Title: Safe Exercise for Age-Related Muscle Loss in Hospitalized Seniors

Summary:

This study compares two exercise methods to help older hospital patients (age 65+) rebuild muscle strength after being diagnosed with sarcopenia (age-related muscle loss). We want to know if using special pressure cuffs during light exercise works better than traditional strength training alone.

Who Can Join:

Hospitalized seniors with stable health conditions Excludes those with severe disabilities, dementia, or certain blood circulation problems

What We'll Do:

40 participants will be randomly assigned to either:

Traditional Training Group:

Uses weights/bands at 65-75% max capacity Arm/leg exercises 3x/week for 4 weeks

Pressure Cuff Training Group:

Uses special cuffs on arms/thighs during lighter exercises (20% max capacity) Same exercise frequency with controlled pressure for safety

What We'll Measure:

Handgrip strength (main test at 0/4/12 weeks) Walking speed, balance tests, quality of life surveys Any side effects like dizziness/nausea

Safety First:

Doctors will check your health before starting. Nurses will monitor every session. We use medical-grade cuffs with safe pressure limits (arm: 80-100mmHg, thigh: 150-200mmHg). You can stop anytime if uncomfortable.

Why This Matters:

This could help hospitalized seniors regain strength faster using gentler exercises. All activities are supervised by rehabilitation specialists at West China Hospital, with ethics committee approval (IRB number required).

Eligibility criteria

Qualifiers

Hospitalized patients aged ≥65 years

Diagnosed with sarcopenia per EWGSOP2019 criteria

Acute medical conditions stabilized for ≥4 weeks (e.g., resolved infections, controlled heart failure)

Disqualifiers

Severe disability (Barthel Index ≤40)

Significant cognitive impairment (MMSE ≤18) or major psychiatric disorders (DSM-5 criteria)

History/predisposition to deep vein thrombosis

Coagulopathy (INR >1.5, platelets <100×10⁹/L)

Trial design

Treatments tested in this trial

  • Blood Flow Restriction Training (BFRT)
  • Conventional Resistance Training (CRT)

Treatment groups

40 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators