This randomized, double-blind clinical trial aims to compare the clinical and imaging effects of autologous bone marrow aspirate versus platelet-rich fibrin injections in patients with chronic plantar fasciitis. The procedures are performed under ultrasound guidance to ensure precision and safety. The study evaluates pain reduction, foot function, and ultrasonographic changes in the plantar fascia at follow-up intervals.
Adults aged 18 to 75 years.
Clinical diagnosis of chronic plantar fasciitis for more than 6 months, confirmed by ultrasonography (increased plantar fascia thickness and hypoechogenicity).
Persistent heel pain refractory to conventional conservative treatment (stretching, orthotics, physical therapy, or corticosteroid injections).
Visual Analog Scale (VAS) pain score ≥ 4 at baseline.
Previous foot or ankle surgery on the affected limb.
Acute trauma, infection, or ulceration in the region of the plantar fascia.
Systemic inflammatory diseases (e.g., rheumatoid arthritis, lupus, psoriatic arthritis).
Metabolic or endocrine disorders interfering with healing (e.g., diabetes mellitus with poor glycemic control, thyroid disorders).