Brain Activity, Cognitive Function, and Walking Ability in Parkinson's Disease

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age40-80
SponsorNational Yang Ming Chiao Tung University

About this trial

The dual-task automated walking performance in people with Parkinson\'s disease (PD) is affected by their gait disturbances and impaired executive functions. Currently, the relationship between brain activity related to inhibitory control, executive functions, and dual-task walking performance in people with PD is not well understood. Therefore, this study aims to investigate the significance of different executive function domains on gait stability in healthy older adults and people with PD; whether brain activation related to inhibitory control is associated with gait stability in healthy older adults and people with PD.

Eligibility criteria

Qualifiers

Diagnoses of idiopathic Parkinson disease

Stable dopaminergic medicine ≥ 2 weeks

Able to walk 10 meters without aid

Mini-Mental Status Examination ≥ 24 points

Disqualifiers

Other medical diagnoses of neurological, musculoskeletal, or cardiopulmonary disorders

History of brain surgery (e.g. deep brain stimulation)

Trial design

Treatments tested in this trial

  • Cognitive function, gait, and electroencephalogram

Treatment groups

70 Participants
are divided into 2 treatment groups