Brain and Behavior Influences on Obesity Development From Infancy Through Childhood
ConditionObesity and Overweight
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age7-12
SponsorJohns Hopkins University
About this trial
The investigators project, RESONATE, aims to investigate why some children develop obesity. To do this it uses data on eating and eating-related behaviors, genetic and environmental factors, and brain structure and function. This data is collected in a sub-sample of RESONANCE, a large study of families of children from infancy through childhood. The results will lay foundations for the development of early interventions to prevent or treat obesity.
Eligibility criteria
Qualifiers
Participants from the RESONANCE cohort are eligible if the participant will reach 7-12 years of age during the proposed project period and have no food allergies.
Disqualifiers
In utero exposure to alcohol, cigarette, or illicit substances;
First trimester fetal US abnormalities;
Complicated pregnancy (e.g., pre-eclampsia);
Complicated delivery, including APGAR scores less than 8 and/or neonatal intensive care unit (NICU) admission;
Trial design
Treatments tested in this trial
- fMRI cue reactivity task
- fMRI go no go task
- Ad libitum meal test
- Eating in the absence of hunger test
Treatment groups
210 Participants
are divided into 1 treatment groupSponsors and collaborators
Johns Hopkins University
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator
Rhode Island Hospital
Collaborator
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Collaborator
University of Washington
Collaborator
Source ClinicalTrials.gov