Brain-based Prediction of the Dying Duration in Humans After Withdrawal of Life Sustaining Therapies to Inform Donation After Circulatory Death

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age19+
SponsorUniversity of British Columbia

About this trial

The purpose of this study is to develop a new tool that uses information collected before life-sustaining treatments are withdrawn to better predict whether a patient will die within the time needed for organ donation to be possible. The tool created should help improve planning for organ donation and provide families and healthcare teams with more accurate information.

Eligibility criteria

Qualifiers

Age ≥ 19;

Eligible for DCD

Disqualifiers

concurrent vasopressor doses of norepinephrine >0.05 mcg/kg/min (or dose equivalent)

PaO2/FiO2 ratio <150 mmHg

complete high cervical spinal cord injury (C5 and above)

cardiac support devices (e.g., ECMO, balloon pump, ventricular assist device)

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

102 Participants
are grouped into 1 trial group

Sponsors and collaborators

University of British Columbia

Lead sponsor

Canadian Institutes of Health Research (CIHR)

Collaborator