Brain Circuitry Therapeutics for Schizophrenia
ConditionSchizophrenia; Psychosis
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorIndrit Begue
About this trial
This project is a double blind randomized clinical trials that examines the efficacy of cerebellar non invasive stimulation for apathy improvement in patients with schizophrenia
Eligibility criteria
Qualifiers
Inclusion criteria
Capable of giving informed consent as evaluated by the treating psychiatrist
Informed Consent signed by the subject
Patients aged 18 - 65 years diagnosed with a schizophrenia spectrum disorder (including schizophrenia, schizoaffective or non-organic psychosis, psychotic disorder NOS) according to DSM-5 criteria
Disqualifiers
Comorbid and clinically active current major depressive episode determined by the treating psychiatrist.
Active psychotic symptoms. In particular, patients that at Baseline have a PANSS scores of more than 4 in any of the following PANSS items: delusions, suspiciousness/persecution and hallucinatory behaviour will be considered not stable enough to participate.
Significant extrapyramidal side-effects quantified by total score of mSAS > 12.
Increased sedation due to use of medication (slowing, drowsiness, slurred speech etc.)
Trial design
Treatments tested in this trial
- iTBS
Treatment groups
70 Participants
are divided into 2 treatment groupsSponsors and collaborators
Indrit Begue
Lead sponsor
University of Geneva, Switzerland
Sponsor institution
University of Geneva, Switzerland
Collaborator
Source ClinicalTrials.gov