Brain Connectivity Changes in Glioma Patients During Treatment
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-64
SponsorJohannes Kepler University of Linz
About this trial
The goal of this observational study is to better understand how the brain changes during the treatment of glioma. In particular, the study looks at changes in important brain areas that are responsible for functions such as movement, language, or sensation, as well as the nerve fiber pathways that connect these areas.
The main question this study aims to answer is:
How do important brain areas and their connections adapt and reorganize over the course of glioma treatment?
Patients with glioma will undergo repeated brain imaging examinations as part of their regular medical care. These images will be analyzed over time to observe changes in brain activity and structure during different stages of therapy.
By studying these changes, researchers hope to gain new insights into the brain's ability to adapt (neuroplasticity) throughout the entire course of glioma treatment.
Eligibility criteria
Qualifiers
Patients with diffuse gliomas (WHO grade 2-4).
Age >18 years and <65 years.
Written participant information and informed consent provided and signed.
Signed informed consent for functional magnetic resonance imaging (fMRI).
Disqualifiers
Age <18 years or >65 years.
Pregnancy.
Active medical implants (e.g., pain pump, defibrillator, cardiac pacemaker),
Orthodontic braces,
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Sponsors and collaborators
Johannes Kepler University of Linz
Lead sponsor
Clinical Research Institute for Neurosciences, JKU Linz, Austria
Collaborator
Institute of Neuroradiology, Kepler University Hospital, Johannes Kepler University, Lin
Collaborator
Department of Neurosurgery, Kepler University Hospital, Johannes Kepler University Linz
Collaborator
Department of Radiation Oncology, Ordensklinikum Linz, Barmherzige Schwestern, Linz, Austria
Collaborator
Source ClinicalTrials.gov