Brain Health in Transgender Adults
ConditionGender Dysphoria
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-45
SponsorUniversity of Wisconsin, Madison
About this trial
The purpose of this study is to test whether and how a person's brain changes in the first few months after starting gender affirming hormone therapy (GAHT). The investigators want to know if GAHT changes: 1) cerebral blood flow (CBF), 2) brain structure, connectivity, and cognitive task performance, and 3) neurocognitive function (memory, attention, executive function, processing speed). 36 male at birth and 36 female at birth participants will conduct baseline studies prior to GAHT, with a second identical set of study visits 4-6 months after GAHT begins.
Eligibility criteria
Qualifiers
intention to undergo GAHT
Disqualifiers
BMI greater than 40 kg/m2
Age greater than 45 yrs
Blood pressure greater than 140/90 (stage II hypertension)
A current diagnosis of type II diabetes
Trial design
Treatments tested in this trial
- Magnetic Resonance Imaging
- Cognition and Health Tests
- Optional Exercise Test
Treatment groups
72 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov