About this trial
In older adults, diminished sensation of the legs and feet is highly prevalent and causes poor balance and reduced mobility. This type of sensation is not only dependent upon the receptors and nerves in the legs and feet, but also upon a complex central nervous system pathway that includes the cerebral cortex of the brain. This project will use a form of noninvasive brain stimulation called transcranial direct current stimulation (tDCS) to test whether increasing the excitability of the brain networks that process sensory feedback can augment foot sole sensation, balance, and mobility in older adults suffering from mild-to-moderate foot sole sensory impairments.
Eligibility criteria
Qualifiers
Aged ≥65 years.
Self-reported feeling of unsteadiness or difficulty when standing and walking.
Mild-to-moderate foot-sole somatosensory impairment: the ability to perceive 75g monofilament but inability to perceive 10g monofilament.
Disqualifiers
self-reported inability to stand or walk continuously for one minute without personal assistance (canes or walkers allowed);
history or presence of foot ulceration, amputation, or deformities;
self-reported uncontrolled pain or pain that is associated with mobility disability;
uncontrolled diabetes mellitus;
Trial design
Treatments tested in this trial
- transcranial direct current stimulation
- active sham stimulation
Treatment groups
Sponsors and collaborators
Hebrew SeniorLife
Lead sponsor
National Institute on Aging (NIA)
Collaborator