Breaking Sitting with High-intensity Interval Training for Brain Health

ConditionAging
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-75
SponsorUniversity of Illinois at Urbana-Champaign

About this trial

This trial will examine whether interrupting 3.5 hours of sitting every 30 min with 6 min high intensity interval training (HIIT) breaks compared to light intensity interval training (LIIT) will improve brain health in cognitively normal older adults. This trial will test the feasibility of HIIT breaks to sitting. It will also address several important but unanswered questions: (1) Does interrupting sitting with short HIIT breaks improve frontoparietal function? (2) Can interrupting sitting with HIIT breaks improve cognitive functions?

Eligibility criteria

Qualifiers

Age 40-75 years

BMI <40 kg/m2

Sedentary (≥ 6 h/day sitting by a survey question)

Physically inactive adults based on the CSEP-PATH: Physical Activity and Sedentayr Behaviour Questionnaire (PASB-Q) Adult (low or medium physical activity range equivalent to less than 300 min of moderate intensity physical activity per week)

Disqualifiers

Physical disability or musculoskeletal disease prohibitive to vigorous exercise

Learning disabilities

Cognitive impairment (MoCA <26)

Type 1 or 2 diabetes

Trial design

Treatments tested in this trial

  • High-Intensity Interval Training (HIIT) Breaks to Sitting
  • Light-Intensity Interval Training (LIIT) Breaks to Sitting

Treatment groups

54 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Illinois at Urbana-Champaign

Lead sponsor

Northeastern University

Collaborator

National Institute on Aging (NIA)

Collaborator