Bufei Yishen Prescription on Patients With Frequent AECOPD in Stable Stage

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-80
SponsorHenan University of Traditional Chinese Medicine

About this trial

To evaluate the clinical efficacy and health economic advantages of Lung Replenishing and Kidney Enhancing Formula for the treatment of patients with frequent acute exacerbations in the stabilized phase.

Eligibility criteria

Qualifiers

Patients diagnosed with COPD at a stable stage.

Stable COPD patients with frequent acute exacerbation.

Age 40-80 years old.

The condition was stable 4 weeks before enrollment.

Disqualifiers

complicity with other diagnosed and clinically significant respiratory diseases, including but not limited to: asthma, active pulmonary tuberculosis, bronchiectasis, pulmonary hypertension, pulmonary embolism, pneumothorax, pleural effusion, interstitial lung disease, or other active pulmonary diseases requiring intervention.

Patients with severe or acute cardiovascular and cerebrovascular diseases (acute cardiovascular and cerebrovascular events, malignant arrhythmias, unstable angina pectoris, cardiac function grade 3 or above, uncontrolled hypertension, etc.).

Complicated with severe liver and kidney disease (severe liver disease refers to cirrhosis, portal hypertension and varicose vein bleeding, serious kidney disease including dialysis, kidney transplantation).

Any item of liver function index (ALT, AST) exceeds the upper limit of normal reference value by 1.5 times, and renal function index Scr exceeds the upper limit of normal reference value.

Trial design

Treatments tested in this trial

  • Bufei Yishen Prescription Granule

Treatment groups

848 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

Henan University of Traditional Chinese Medicine

Lead sponsor

The First Affiliated Hospital of Henan University of Traditional Chinese Medicine

Collaborator

The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine

Collaborator