By Assessing the Continuous Respiratory Physiological Changes Through Prone Position, Determine the Optimal Duration for Prone Position

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorNational Taiwan University Hospital

About this trial

The prone position leads to a more homogeneous distribution of ventilation by inflation of collapsed alveoli and reduction in alveolar hyperinflation. By employing EIT, the study can obtain a thorough comprehension of the ongoing alterations in regional ventilation before and after adopting the prone position. It is also anticipated that there is an impact on inflammation biomarkers before and after the prone position. This assessment aids in determining the ideal duration for prone position therapy, encompassing the necessary hours and days in the prone position.

Eligibility criteria

Qualifiers

Acute respiratory distress syndrome

Age > 18

Serial arterial blood gas data:PaO2/FiO2 <150. The mechanical ventilator setting:FiO2>0.6, PEEP>5 cmH2O

Disqualifiers

Implantable electronic devices (e.g., pacemakers)

Body mass index > 30

Major thoracic and abdominal surgery

Patients with unstable spine and pelvis conditions

Trial design

Treatments tested in this trial

  • Electrical Impedance Tomography

Treatment groups

No treatment groups listed