C-Protein in Fatigue and Aging
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorUniversity of Oregon
About this trial
This study is investigating changes to the proteins in skeletal muscle that contribute to reduced muscle size and muscle function that occurs with aging.
Eligibility criteria
Qualifiers
Adults between the ages 18-35 or 65-80 years
Healthy by self-report
Willing to participate in all aspects of the study design including muscle biopsy, unilateral exercise, and physical activity monitoring
Fluent in English (due to lack of translation services, it is not practical to conduct the study using a language other than English).
Disqualifiers
Orthopaedic limitation (severe knee osteoarthritis, prior joint replacement, etc.).
Volunteer has dementia or related mental issues that potentially put the subject at risk as determined by prior diagnosis.
Volunteer has known untreated endocrine disease (hypo/hyper thyroidism, Addison's Disease or Cushing's syndrome, etc.)
Volunteer has untreated/poorly-controlled hypertension (stage 2, per American College of Cardiology [>140/90 mmHg]).
Trial design
Treatments tested in this trial
- Fatiguing Exercise
Treatment groups
24 Participants
are divided into 1 treatment groupSponsors and collaborators
University of Oregon
Lead sponsor
Wu Tsai Human Performance Alliance
Collaborator
National Institutes of Health (NIH)
Collaborator
Oregon Health and Science University
Collaborator
Washington State University
Collaborator
National Institute on Aging (NIA)
Collaborator
Source ClinicalTrials.gov