CADASIL Registry Study
ConditionCadasil
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-85
SponsorBin Cai
About this trial
The aim of this study is to determine the clinical spectrum and natural progression of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) and related disorders in a prospective multicenter study, to assess the clinical, genetic and epigenetic features of patients with CADASIL , to optimize clinical management.
Eligibility criteria
Qualifiers
Sign informed consent.
Age>18
Clinical diagnosis of patients with CADASIL,and confirmed by genetic test or skin biopsy
Asymptomatic NOTCH3 mutation carriers
Disqualifiers
Unable to cooperate with inspectors
Serious systemic illness, such as heart, liver, kidney disease or major mental illness
Contraindications for imaging examination
Trial design
Treatments tested in this trial
- Not listed
Trial groups
1,000 Participants
are grouped into 4 trial groupsSponsors and collaborators
Bin Cai
Lead sponsor
First Affiliated Hospital of Fujian Medical University
Sponsor institution
Source ClinicalTrials.gov