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CALLY Index, Frailty and SOFA-2 for Mortality Prediction in Geriatric ICU Patients

ConditionsCritical IllnessFrailtyIntensive Care Unit (ICU)
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65+
SponsorIstanbul University - Cerrahpasa

About this trial

This study aims to evaluate the prognostic value of the C-reactive protein-albumin-lymphocyte (CALLY) index, Clinical Frailty Scale (CFS), and SOFA-2 score in predicting mortality among geriatric intensive care unit (ICU) patients.

The primary outcome is ICU mortality. Secondary outcomes include 28-day mortality, ICU length of stay, duration of mechanical ventilation, need for renal replacement therapy, and vasopressor requirement.

The study also investigates whether the combined use of these parameters improves predictive performance compared to conventional scoring systems such as APACHE II.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age ≥65 years

Admission to the intensive care unit

Availability of required clinical and laboratory data within the first 24 hours of ICU admission

Disqualifiers

Death within the first 24 hours after ICU admission

Missing key clinical or laboratory data

Terminal malignancy receiving palliative care

Trial population

Geriatric patients (aged ≥65 years) admitted to the intensive care unit.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • observational study

    Other intervention

    No intervention is applied.This is an observational study in which patients receive standart clinical care.

Treatment groups

100 Participants
are divided into 1 treatment group
Group A: Geriatric ICU patients1 intervention

Trial outcomes

Primary outcomes

1

ICU Mortality

All-cause mortality occurring during the intensive care unit stay.

Time frame
From ICU admission until ICU discharge or death, assessed up to 28 days

Secondary outcomes

1

28-day Mortality

All-cause mortality within 28 days after ICU admission.

Time frame
28 days
2

ICU Length of Stay

Duration of stay in the intensive care unit, measured in days.

Time frame
From ICU admission until ICU discharge or death, assessed up to 28 days
3

Hospital Length of Stay

Total length of hospital stay, measured in days.

Time frame
From hospital admission until hospital discharge or death, assessed up to 28 days
4

Duration of Mechanical Ventilation

Total duration of invasive mechanical ventilation, measured in days.

Time frame
From initiation of invasive mechanical ventilation until discontinuation, assessed up to 28 days

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Istanbul University - Cerrahpasa

Lead sponsor

Başakşehir Çam & Sakura City Hospital

Sponsor institution

Source ClinicalTrials.gov
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