Cannabis Reduction and Functional Outcomes

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMedical University of South Carolina

About this trial

This study evaluates the effects of cannabis use reduction among adults diagnosed with cannabis use disorder (CUD). Participants will undergo an 8-week intervention combining motivational interviewing, computerized cognitive behavioral therapy (CBT4CBT), and financial incentives for reduction in urinary cannabinoids. The study aims to assess improvements in cannabis-related problems, sleep, cognitive performance, CUD severity, and quality of life.

Eligibility criteria

Qualifiers

Age 18+

Urinary cannabinoid level ≥ 50 ng/mL

DSM-5 diagnosis of CUD (mild, moderate, or severe)

Willingness to attempt cannabis reduction

Disqualifiers

Serious medical/psychiatric conditions

Pregnancy or breastfeeding

Use of cannabis in past 30 days was for medical purposes only

Discontinuation or reduction of cannabis use may exacerbate a pre-existing condition

Trial design

Treatments tested in this trial

  • CBT4CBT (Computerized Cognitive Behavioral Therapy)
  • Motivational Interviewing
  • Contingency Management

Treatment groups

No treatment groups listed

Sponsors and collaborators

Medical University of South Carolina

Lead sponsor

National Institutes of Health (NIH)

Collaborator

National Institute on Drug Abuse (NIDA)

Collaborator