CAPABLE Transplant
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-99
SponsorJohns Hopkins University
About this trial
The purpose of this mixed methods study is to adapt CAPABLE as CAPABLE Transplant to accomplish two things: 1) To resolve barriers to being classified as active on the Kidney Transplant (KT) waitlist, 2) as a surgical prehabilitation intervention targeting the pre-frail/ frail KT waitlist population. It consists of two phases- an open label pilot and a randomized waitlist control trial, and 3) pilot test the feasibility and acceptability for CAPABLE Transplant in symptom and waitlist specific metrics amongst low-income active kidney transplant waitlist candidates.
Eligibility criteria
Qualifiers
Deceased Donor Waitlist
≥18 years old
Community dwelling
Current Inactive status or active and had been inactive in the last 18 months for cardiovascular disease, frailty, obesity, social support, mental health, incomplete testing OR Active on the waitlist and low-income
Disqualifiers
Living Donor Waitlist
Severe cognitive impairment
Inactivity expected to last > 3 months (eg cancer treatment)
>4 hospitalizations in the last 12 months
Trial design
Treatments tested in this trial
- CAPABLE Transplant- Open Label Pilot
- CAPABLE Transplant- Randomized Control Trial
Treatment groups
43 Participants
are divided into 3 treatment groupsSponsors and collaborators
Johns Hopkins University
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator
Source ClinicalTrials.gov