Capturing Autobiographical Memory Formation in Real World Spaces Using Multimodal Recordings

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Utah

About this trial

The goal of this observational study is to develop novel methods for integrating multimodal data streams with invasive neural recordings to study autobiographical memory (AM) formation in individuals with implanted neurostimulation devices (e.g., NeuroPace RNS) for epilepsy treatment. The main questions it aims to answer are:

How does the brain encode and retrieve real-world autobiographical memories? Can multimodal data integration enhance our understanding of memory-related cognitive and neural mechanisms?

Participants will:

* Use a smartphone-based recording application (CAPTURE app) to collect real-world data. * Have their wearable sensor data (e.g., audio-visual, accelerometry, GPS, autonomic physiology, eye tracking) synchronized with invasive neural recordings.

Researchers will analyze these multimodal data streams to develop new analytic approaches for studying memory formation in naturalistic settings, with the long-term goal of informing neuromodulation-based memory enhancement treatments for individuals with memory disorders.

Eligibility criteria

Qualifiers

18 years of age or older

healthy to minor cognitive impairment

Disqualifiers

younger than 18 years of age

more than minor cognitive impairment

Trial design

Treatments tested in this trial

  • Free and Cued Recall Memory. Temporal Sequence and Spatial Memory

Treatment groups

50 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Utah

Lead sponsor

National Institutes of Health (NIH)

Collaborator

National Institute of Mental Health (NIMH)

Collaborator

University of California, San Diego

Collaborator

University of California, Los Angeles

Collaborator