CAR-T Treatment in Pediatric and Adult Acute Lymphoblastic Leukemia
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorGruppo Italiano Malattie EMatologiche dell'Adulto
About this trial
The goal of this observational study is to evaluate the efficacy of the treatment with approved CAR-T cells in Italy in pediatric and adult patients with acute B-cell lymphoblastic leukemia. The main question it aims to answer is:
which is the overall response rate in pediatric and adult patients with acute B-cell lymphoblastic leukemia treated with approved CAR-T cells?
Data will be extracted from patients medical records.
Eligibility criteria
Qualifiers
Diagnosis of ALL R/R CD19+
Patients are pediatric (all patients up to the age of 18) adult (all comers older than 18)
Prescribed treatment with Tisagenlecleucel or Brexucabtagene autoleucel as per approved AIFA criteria, or obecabtagene autoleucel - as well as other products - when available
Provided consent (or did not opposed) for collection and use of patient data per local regulations
Disqualifiers
None
Trial design
Treatments tested in this trial
- Not listed
Trial groups
107 Participants
are grouped into 1 trial groupLocations
Sponsors and collaborators
Source ClinicalTrials.gov