Cardiac-Control Affecting Learning Through Mindfulness (CALM)
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50-70
SponsorUniversity of Southern California
About this trial
Some types of meditation lead heart rate to become more steady as breathing quiets whereas others lead to large heart rate swings up and down (oscillations) as breathing becomes deeper and slower. The current study is designed to investigate how daily mindfulness practice with heart rate biofeedback during breathing in a pattern that either increases or decreases heart rate oscillation affect attention and memory and blood biomarkers associated with Alzheimer's disease.
Eligibility criteria
Qualifiers
Fluent in English
Black/African-American or White/European-American
Aged between 50-70 years old
Non-pregnant and non-menstruating (for at least the past year)
Disqualifiers
Have a disorder that would impede performing the breathing intervention (e.g., abnormal cardiac rhythm, arrhythmia, dyspnea)
Have cognitive impairment
Have regularly played Lumosity games in the past 6 months
Have any conditions listed below that are not safe for MRI
Trial design
Treatments tested in this trial
- Daily practice
Treatment groups
240 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Southern California
Lead sponsor
University of California, Irvine
Collaborator
National Institute on Aging (NIA)
Collaborator
Source ClinicalTrials.gov