Cardiac Injury Due to Anthracycline in Paediatric Oncological Patients

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age0-18
SponsorIRCCS Burlo Garofolo

About this trial

The study investigates the role of echocardiography and of serum biomarkers (NT-proBNP, cardiac Troponin-I) in predicting cardiac injury in a cohort of paediatric oncological patients treated with Anthracycline chemotherapy.

Eligibility criteria

Qualifiers

Paediatric oncological patients 0-18 years

Planned start of anthracycline therapy

Normal left ventricular systolic function according to International Guidelines before the treatment with AC

Disqualifiers

Previous anthracycline treatment, bone marrow transplantation or chest radiation

More than mild pericardial effusion

More than mild mitral regurgitation

Poor echocardiographic acoustic window

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

22 Participants
are grouped into 1 trial group

Sponsors and collaborators