Cardioneuroablation vs Pulmonary Vein Isolation in Treatment of Paroxysmal Atrial Fibrillation

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSt. Joseph's Centre, Poland

About this trial

The goal of this study is to compare effectiveness of cardioneuroablation of right anterior ganglionated plexus and pulmonary vein isolation in patients with enhanced vagal tone expressed as deceleration capacity \>7.5ms.

Eligibility criteria

Qualifiers

Paroxysmal atrial fibrillation documented in ECG or Holter monitoring

Deceleration capacity >7.5ms

Life expectancy more than 1 year

Age ≥18 years

Disqualifiers

Permanent AF lasting more than one year or persistent AF lasting more than 7 days

AF secondary to electrolyte imbalance, thyroid disease, alcohol abuse, or other non-heart related causes

Anteroposterior dimension of the left atrium in the echocardiography ≥43mm

Clinically significant arrhythmias other than AF

Trial design

Treatments tested in this trial

  • Cardioneuroablation of right anterior ganglionated plexus
  • Pulmonary vein isolation

Treatment groups

160 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators