Cardiopulmonary Exercise Testing in Cardiosurgery Patients

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorSt. Anne's University Hospital Brno, Czech Republic

About this trial

Cardiopulmonary exercise testing (CPET) is considered to be a gold standard in pre-operative risk assessment and stratification of high risk patients scheduled for major surgery. Surprisingly, only a limited number of studies examined the prognostic role of CPET in cardiothoracic surgery. This is in contrast with rather poor discriminating quality of cardiovascular surgery risk scores and predominantly elderly cardiovascular surgery patients, with significant comorbidity and high degree of frailty. Recently, CPET was shown feasible in coronary artery bypass grafting surgery candidates. Additionally, the rest parameter, which is the partial pressure of end-tidal carbon dioxide (PETCO2) and a submaximal exercise parameter (the VE/VCO2 slope) with good prognostic utility across multiple respiratory exchange ratio values), has been shown to predict mortality and post-operative complications.

Whether these rest and submaximal exercise parameters can be used to predict postoperative complications in cardiovascular surgery patients is yet to be determined.

Eligibility criteria

Qualifiers

patients scheduled for coronary artery bypass graft surgery

Disqualifiers

not able to perform cardiopulmonary exercise testing, off-pump revascularization, without full sternotomy, previous cardiac surgery

Trial design

Treatments tested in this trial

  • Cardiopulmonary exercise testing

Treatment groups

130 Participants
are divided into 1 treatment group

Sponsors and collaborators

St. Anne's University Hospital Brno, Czech Republic

Lead sponsor

Centre of Cardiovascular and Transplantation Surgery, Czech Republic

Collaborator