CARE-CP (Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients With Chest Pain)

ConditionChest Pain
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21+
SponsorWake Forest University Health Sciences

About this trial

The goal of this study is to determine if rapid outpatient evaluation vs hospitalization management is the best strategy (based on patient-centered measures and safe, equitable, and efficient resource use) for evaluating patients with acute chest pain who are at moderate risk for acute coronary syndrome (ACS). Patients will be randomized in the Emergency Department to either an outpatient evaluation (CARE-CP) or hospitalization evaluation for their symptoms.

Eligibility criteria

Qualifiers

Age ≥21 years old

Chest pain or Symptoms of acute coronary syndrome (ACS)

Moderate risk of ACS (all of the below)

Hear Score 4-6

Disqualifiers

ST Elevation Myocardial Infarction (STEMI) Activation

ST Changes or new T-wave inversions ≥1mm on ECG

Any Elevated Troponin Measure (Based on Sex-Specific 99th Percentile)

Serial change between Troponin Measures (Delta) ≥5 pg/mL

Trial design

Treatments tested in this trial

  • Outpatient Evaluation
  • Hospitalization Evaluation

Treatment groups

502 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Wake Forest University Health Sciences

Lead sponsor

Agency for Healthcare Research and Quality (AHRQ)

Collaborator