About this trial
The goal of this study is to determine if rapid outpatient evaluation vs hospitalization management is the best strategy (based on patient-centered measures and safe, equitable, and efficient resource use) for evaluating patients with acute chest pain who are at moderate risk for acute coronary syndrome (ACS). Patients will be randomized in the Emergency Department to either an outpatient evaluation (CARE-CP) or hospitalization evaluation for their symptoms.
Eligibility criteria
Qualifiers
Age ≥21 years old
Chest pain or Symptoms of acute coronary syndrome (ACS)
Moderate risk of ACS (all of the below)
Hear Score 4-6
Disqualifiers
ST Elevation Myocardial Infarction (STEMI) Activation
ST Changes or new T-wave inversions ≥1mm on ECG
Any Elevated Troponin Measure (Based on Sex-Specific 99th Percentile)
Serial change between Troponin Measures (Delta) ≥5 pg/mL
Trial design
Treatments tested in this trial
- Outpatient Evaluation
- Hospitalization Evaluation
Treatment groups
Sponsors and collaborators
Wake Forest University Health Sciences
Lead sponsor
Agency for Healthcare Research and Quality (AHRQ)
Collaborator