About this trial
The purpose of this research study is to better understand how stress, sleep and activity might impact caregivers' mood and brain health. This study includes a randomized experimental component where therapists will systematically deliver one of two evidence-based talk-therapy treatments. The aim is to evaluate effects on meaningful health-relevant measures including morning activation levels, depression symptoms, rumination, and aspects brain connectivity previously linked with depression. Participants will complete surveys about their caregiving experiences, health, and mood, undergo an MRI, and wear an actigraphy watch that measures activity levels throughout the day and when sleeping.
Eligibility criteria
Qualifiers
Age 55 years or older.
Provide at least 15 hours/week of unpaid care to a patient with a dementia diagnosis.
Reporting stress or strain delivering care
No or stable pharmacotherapy for depression
Disqualifiers
Unsafe or unable to undergo MRI
Active Cognitive Behavioral Therapy for mood or insomnia
Probable dementia diagnosis
Deadly illness or plans to leave the study area
Trial design
Treatments tested in this trial
- Morning Action Plan Execution
- Activity Strategy-based Session with Therapist
- Attention-based Session with Therapist
- Advance sleep-wake time
Treatment groups
Sponsors and collaborators
University of Pittsburgh
Lead sponsor
National Institute of Mental Health (NIMH)
Collaborator