The purpose of this study is to evaluate the effectiveness of two models of cascade testing in identifying at-risk family members of individuals diagnosed with familial hypercholesterolemia (FH).
Age ≥ 18 years.
Confirmed FH diagnosis using Dutch Lipid Clinic Network criteria *or* genetic confirmation.
Identified through REP or Tapestry databases.
Able and willing to provide informed consent.
No confirmed FH diagnosis.
Insufficient clinical follow-up (<5 years).
No identifiable or contactable relatives.
Prior participation in structured cascade testing.