Castor Oil Ingestion and Balloon Catheter for Labor Induction in Nulliparous

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-60
SponsorHoly Family Hospital, Nazareth, Israel

About this trial

The goal of this randomized controlled trial is to examine the efficacy of combining castor oil ingestion with extra-amniotic single balloon catheter for cervical ripening on time from induction to delivery in nulliparous women.

The main question it aims to answer are:

Does the addition of the use of castor oil to extra-amniotic single balloon reduce the time until birth? Does the addition of the castor oil affect other perinatal outcomes during childbirth? Are the side effects of the castor tolerated by the mothers? Participants will be randomly divided into 2 groups: the study group will drink a mixture of 60 ml of castor oil mixed with 140 ml of orange juice. Thirty minutes later, an extra-amniotic single balloon catheter will be inserted above the internal cervical os and filled with 60 mL of normal saline. In the control group, a foley catheter will be inserted into cervical canal without ingestion of castor oil.

Eligibility criteria

Qualifiers

Women above 18 years old

Sign an informed consent

Term pregnancy (>37 weeks)

Viable fetus

Disqualifiers

Previous cesarean delivery

Major fetal malformations

Contraindication to spontaneous vaginal delivery

Amniotic fluid index >25cm

Trial design

Treatments tested in this trial

  • Induction of labor

Treatment groups

142 Participants
are divided into 2 treatment groups